Frequency of Depression in Patients With Diabetes Mellitus Presenting to DHQ Kohat

Syed Atta  Ullah; Arif  Mumtaz; Abdul  Jalil Khan; Ismail  Khan; Wajid  Ali; Muhammad Hassam  Khan

doi:10.54112/bcsrj.v6i12.2114

Authors

Syed Atta Ullah Department of Medicine, DHQ Teaching Hospital, Kohat, Pakistan
Arif Mumtaz Department of Medicine, DHQ Teaching Hospital, Kohat, Pakistan
Abdul Jalil Khan Department of Family Medicine, Khyber Medical University, Peshawar, Pakistan
Ismail Khan Department of Paediatrics, Mardan Medical Complex, Mardan, Pakistan
Wajid Ali Department of Medicine, DHQ Teaching Hospital, Kohat, Pakistan
Muhammad Hassam Khan Department of Family Medicine, Khyber Medical University, Peshawar, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i12.2114

Keywords:

Depression, Diabetes Mellitus, PHQ-9, Comorbidity

Abstract

Depression is a common but underrecognized comorbidity in patients with diabetes mellitus and adversely affects glycemic control, treatment adherence, and overall quality of life. Objective: To determine the frequency of depression in patients with diabetes mellitus presenting to DHQ Kohat. Methods: This study was conducted in 213 diabetic patients aged 18 to 75 years with HBA1c> 6.5%. The frequency of depression in these diabetic patients was determined. Depression was diagnosed using the PHQ-9 tool and DSM-IV. SPSS 27 was used for analysing the data. Depression was stratified by various demographic and comorbidities using the chi-square test, with a P-value set at ≤ 0.05. Results: The mean age of the patients was 44.62 ± 16.45 years. There were 133 (62.4%) male and 80 (37.6%) female patients. The frequency of depression was 37.6% (n = 80). Depression was significantly associated with female gender, lower economic background, poor glycemic control, hypertension and prolonged diabetes duration. Conclusion: The frequency of depression in patients with diabetes mellitus in our study was 37.6%, and it was notably associated with female gender, lower economic background, poor glycemic control, hypertension and prolonged diabetes duration.

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References

Poznyak A, Grechko AV, Poggio P, Myasoedova VA, Alfieri V, Orekhov AN. The diabetes mellitus-atherosclerosis connection: the role of lipid and glucose metabolism and chronic inflammation. Int J Mol Sci. 2020;21(5):1835. https://doi.org/10.3390/ijms21051835

Balaji R, Duraisamy R, Kumar MP. Complications of diabetes mellitus. Drug Invent Today. 2019;12(1):1-7.

Jing X, Chen J, Dong Y, Han D, Zhao H, Wang X, et al. Related factors of quality of life of type 2 diabetes patients: a systematic review and meta-analysis. Health Qual Life Outcomes. 2018;16(1):189. https://doi.org/10.1186/s12955-018-1021-9

Fischer S, Morales-Suárez-Varela M. The bidirectional relationship between gestational diabetes and depression in pregnant women. Healthcare (Basel). 2023;11(3):404. https://doi.org/10.3390/healthcare11030404

Alva ML. Co-occurrence of diabetes and depression in the US. PLoS One. 2020;15(6):e0234718. https://doi.org/10.1371/journal.pone.0234718

Engidaw NA, Wubetu AD, Basha EA. Prevalence of depression and its associated factors among patients with diabetes mellitus at Tirunesh-Beijing General Hospital, Addis Ababa, Ethiopia. BMC Public Health. 2020;20(1):266. https://doi.org/10.1186/s12889-020-8360-2

Shi Y, Luan D, Song R, Zhang Z. Value of peripheral neurotrophin levels for the diagnosis of depression and response to treatment: a systematic review and meta-analysis. Eur Neuropsychopharmacol. 2020;41:40-51. https://doi.org/10.1016/j.euroneuro.2020.09.633

Ahmad A, Abujbara M, Jaddou H, Younes NA, Ajlouni K. Anxiety and depression among adult patients with diabetic foot: prevalence and associated factors. J Clin Med Res. 2018;10(5):411-416. https://doi.org/10.14740/jocmr3352w

Lin EH, Rutter CM, Katon WJ. The association of depression with the risk of diabetes in a large cohort of patients. Arch Gen Psychiatry. 2005;62(3):298-303.

Thour A, Das S, Sehrawat T, Gupta Y. Depression among patients with diabetes mellitus in North India evaluated using Patient Health Questionnaire-9. Indian J Endocrinol Metab. 2015;19(2):252-255. https://doi.org/10.4103/2230-8210.152793

Kumar B, Junejo J, Dhingra LC, Ahmed Z, Awan I, Dars JA. Frequency of depression in patients with diabetes mellitus. Med Forum. 2021;32(4):83-85.

Riaz M, Imran N, Fawwad A, Basit A. Frequency of depression among patients with type I diabetes in a developing country, Pakistan. Pak J Med Sci. 2017;33(6):1318-1323. https://doi.org/10.12669/pjms.336.13911

Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care. 2001;24(6):1069-1078. https://doi.org/10.2337/diacare.24.6.1069

Accinelli RA, Arias KB, Leon-Abarca JA, López LM, Saavedra JE. Frequency of depression and quality of life in patients with diabetes mellitus in public health facilities of Metropolitan Lima. Rev Colomb Psiquiatr (Engl Ed). 2021;50(4):243-251. https://doi.org/10.1016/j.rcpeng.2021.10.001

Nasir Y, Khan QU. Frequency of depressive symptoms in patients with diabetes mellitus. Pak J Physiol. 2018;14(2):31-33. https://doi.org/10.69656/pjp.v14i2.204

Sana MA, Kashif N, Azam K. Frequency of depression in patients with type 2 diabetes mellitus. Pak Armed Forces Med J. 2022;72(6):1949-1952. https://doi.org/10.51253/pafmj.v72i6.6227